2D Simulation of Cardiac Tissue
A two-dimensional atrial tissue model has been constructed in COMSOL Multiphysics® software to study the propagation of action potential and electrograms. The model presents the atrial electrograms recorded with a mapping catheter.
A 2D atrial tissue model is simulated using the Courtemanche et al. cell model equations. PDE in coefficient form was used in COMSOL Multiphysics® to reproduce the propagation of action potential. Total of 21 nonlinear differential equations solved between MATLAB® and COMSOL.
The model is capable of being modified to study the effects of recording electrode size and location on electrograms. It also can be modified to study the action potential propagation during atrial ablation therapy.