Simulating Microbubble Flows Using COMSOL Multiphysics

X. Chen[1], and S. Ghadiali[1,2]

[1]Mechanical Engineering and Mechanics, Lehigh University, Bethlehem, PA, USA
[2]Bio Engineering program, Lehigh University, Bethlehem, PA, USA
发布日期 2008

Acute respiratory distress syndrome (ARDS) is a severe lung disease caused by a variety of direct and indirect insults. The main treatment for ARDS is mechanical ventilation. The ventilation of fluid filled lungs involves the propagation of microbubbles over a layer of epithelial cells.

We utilized COMSOL® with MATLAB® to develop a time dependent computational model of semi-infinite air bubble progression in a liquid filled channel. As a result, we are able to obtain very accurate and stable solutions at very small capillary numbers compared to other methods during the simulation of the air liquid bubble interface movement.