论文和技术资料

Singlet oxygen (¹O₂) is the major cytotoxic agent during type-II photodynamic therapy (PDT). The production of ¹O₂ involves the complex reactions among cancer agent, oxygen molecule, and treatment laser light. The light propagation in tumor tissue is described by the diffusion equation. In this work, an optimization routine is developed to fit the [¹O₂]_rx profile to the simulated necrosis distance. In this work, a COMSOL based singlet oxygen model is developed for photodynamic therapy.