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Simulating Light Propagation during I-PDT of Locally Advanced Head and Neck Cancer

E. Oakley [1], H. Arshad [1], G. Shafirstein [1],
[1] Roswell Park Cancer Institute, Buffalo, NY, USA
发布日期 2016

Interstitial photodynamic therapy (I-PDT) can be applied for the treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The complex anatomy of LA-HNSCC requires careful planning of the light delivery and fiber insertion. We have developed an image-based approach, using finite element analysis, to suggest the number and location of treatment fibers needed for I-PDT and to calculate the delivered light dose. This finite element model for computing light propagation has the potential to aid in the pretreatment planning and real-time monitoring of I-PDT of LA-HNSCC.

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