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Bioscience and Bioengineering

Microstimulation in The Brain: Does Microdialysis Inuence the Activated Volume of Tissue?

D. Krapohl[1][3], S. Loeffler[2], A. Moser[2], and U.G.Hofmann[1]

[1]Institute for Signalprocessing, University of Luebeck, Lübeck, Germany
[2]Institute for Neurology, University of Luebeck, Lübeck, Germany
[3]Department of Information Technology and Media, Mid Sweden University, Sundsvall, Sweden

Deep Brain Stimulation (DBS) has been established as an effective treatment for Parkinson's disease and other ... 扩展阅读

Modeling Interface Response in Cellular Adhesion

G. Megali[1], D. Pellicanò[1], M. Cacciola[1], F. Calarco[1], D. De Carlo[1], F. Laganà[1], and F.C. Morabito[1]

[1]DIMET Department, Faculty of Engineering, University “Mediterranea” of Reggio Calabria, Reggio Calabria, Italy

Constitutive properties of living cells are able to withstand physiological environment as well as mechanical ... 扩展阅读

Design and Simulation of a Microscale Magnetophoretic Device for the Separation of Nucleated Fetal Red Blood Cells from Maternal Blood

G. Schiavone[1], D.M. Kavanagh[2], and M.P.Y Desmulliez[2]

[1]Politecnico di Torino, Torino, Italy
[2]MIcroSystems Engineering Centre, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh, Scotland, United Kingdom

Intense research has been carried out into methods that aim at harvesting fetal cells from maternal blood as ... 扩展阅读

Modeling the Behavior of Phased Arrays in Brain Tissue: Application to Deep Brain Stimulation

V. Valente[1], A. Demosthenous[1], and R. Bayford[2]

[1]Department of Electronic & Electrical Engineering, University College London, London, United Kingdom
[2]Department of Natural Sciences, Middlesex University, London, United Kingdom

Deep Brain Stimulation (DBS) is a therapeutic tool used for a number of neurological disorders including ... 扩展阅读

Impedance Spectroscopy and Cell Constant of the Electrodes for Deep Brain Stimulation

E. Vinter[1], S. Petersen[1], J. Gimsa[2], and U. van Rienen[1]

[1]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
[2]Institute of Biology, University of Rostock, Rostock, Germany

To achieve a deeper understanding of the mechanism of the Deep Brain Stimulation (DBS) scientists use more ... 扩展阅读

Thin Membrane Modelling for the Electrical Stimulation of Auditory Nerve

A. Grünbaum[1], S. Petersen[1], H.W. Pau[2], and U. van Rienen[1]

[1]IEF funded by DFG Research Training Group 1505/1 Welisa, University of Rostock, Rostock, Germany
[2]Otolaryngology “Otto Körner”, University of Rostock, Rostock, Germany

Modeling of 2-5 μm thin membranes into a cochlea with a width of 2 cm is computationally. The paper is ... 扩展阅读

3D-Simulation of Action Potential Propagation in a Squid Giant Axon

R. Appali[1], S. Petersen[1], J. Gimsa[2], and U. Rienen[1]
[1] Institute of General Electrical Engineering, Chair of Electromagnetic Field Theory, University of Rostock, Germany
[2] Institute of Biology, Chair of Biophysics, University of Rostock, Germany

Study of neurons plays a key role in the fields of basic and medical research aiming at the development of ... 扩展阅读

Local Electroporation of Single Adherent Cells by Micro-Structured Needle Electrodes

K. K. Sriperumbudur[1], P. J. Koester[1], M. Stubbe[1], C. Tautorat[1], J. Held[2], W. Baumann[1], and J. Gimsa[1]
[1] University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
[2] Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany

In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the ... 扩展阅读

Stochastic Modeling of Biological Systems – Ranking the Model Parameters of the Human Vocal Folds

D. Cook[1]
[1]New York University, New York, USA

Computational models of biological systems are becoming more and more common in medical research areas. ... 扩展阅读

Numerical Simulation of the Functional Electromagnetic Stimulation of the Human Femoral Bone using COMSOL

Y. Haba[1], W. Kröger[2], H. Ewald[2], R. Souffrant[1], W. Mittelmeier[1], and R. Bader[1]

[1]Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, University of Rostock, Rostock, Germany
[2]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany

In the present study we determined the relative conductivities and permittivities of fresh cortical and ... 扩展阅读

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