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Bioscience and Bioengineering

Local Electroporation of Single Adherent Cells by Micro-Structured Needle Electrodes

K. K. Sriperumbudur[1], P. J. Koester[1], M. Stubbe[1], C. Tautorat[1], J. Held[2], W. Baumann[1], and J. Gimsa[1]
[1] University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
[2] Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany

In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the ... 扩展阅读

Optimal PDE Control Using COMSOL Multiphysics

I. Neitzel[1], U. Prüfert[2], and T. Slawig[3]

[1]Technische Universität Berlin / SPP 1253
[2]Technische Universität Berlin / Matheon
[3]Excellence Cluster The Future Ocean, Algorithmic Optimal Control - Oceanic CO2-Uptake/SPP 1253

An optimal control problem (OCP) is studied to a PDE of elliptic type as well as state constraints. The ... 扩展阅读

Coupled Electromagnetics-Multiphase Porous Media Model for Microwave Combination Heating

V. Rakesh, and A. Datta
Dept. of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA

Although microwave heating has been studied in great detail, microwave combination heating has not. This work ... 扩展阅读

Hemodynamic Therapy of Middle Cerebral Artery Vasospasm Guided by a Multiphase Model of Oxygen Transport

S. Conrad[1,2], P. Chittiboina[3], and B. Guthikonda[3]

[1]Department of Bioinformatics and Computational Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
[2]Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
[3]Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA

Cerebral vasospasm is a complication of subarachnoid hemorrhage and other neurosurgical emergencies that ... 扩展阅读

Simulating Microbubble Flows Using COMSOL Multiphysics

X. Chen[1], and S. Ghadiali[1,2]

[1]Mechanical Engineering and Mechanics, Lehigh University, Bethlehem, PA, USA
[2]Bio Engineering program, Lehigh University, Bethlehem, PA, USA

Acute respiratory distress syndrome (ARDS) is a severe lung disease caused by a variety of direct and ... 扩展阅读

Modeling of Respiratory Lung Motion as a Contact Problem of Elasticity Theory

R. Werner, J. Ehrhardt, and H. Handels
University Medical Center Hamburg-Eppendorf, Germany

Breathing motion is a major problem in radiotherapy of lung tumors. The development of techniques to ... 扩展阅读

Coupled Fluid-Structural Analysis of Heart Mitral Valve

A. Avanzini, and G. Donzella
Department of Mechanical and Industrial Engineering, University of Brescia, Brescia, Italy

The mitral valve apparatus is a complex and refined mechanism located between the left atrium and the left ... 扩展阅读

Virtual Thermal Ablation in the Head and Neck using COMSOL Multiphysics

U. Topaloglu[1], Y. Yan[2], P. Novak[2], P. Spring[3], J. Suen[3], and G. Shafirstein[3]
[1] Department of Information Technology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
[2]Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
[3]Department of Otolaryngology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

Thermal ablation in the head and neck requires accurate thermal dose delivery to target tissue while ... 扩展阅读

Simulating Hodgkin-Huxley-like Excitation using Comsol Multiphysics

J. Martinek[1,2], Stickler[2] , Reichel[1], and Rattay[2]
[1]Department of Biomedical Engineering and Environmental Management, University of Applied Sciences Technikum Wien, Vienna, Austria
[2]Institute for Analysis and Scientific Computing, Vienna University of Technology, Austria

Most simulations concerning electrical activation of human muscles are based on the modeling approach of ... 扩展阅读

Modeling of snRNP Motion in the Nucleoplasm

M. Blaziková[1], J. Malínský[2], D. Stanek[3], and P. Herman[1]
[1]Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
[2]Institute of Experimental Medicine, Prague, Czech Republic
[3]Institute of Molecular Genetics, Prague, Czech Republic

Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre ... 扩展阅读

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